![]() ![]() Many families with twins claim they have an abnormal number of identical twins in their family tree, despite being told it’s a random event. There is a popular theory (although I have struggled to find any scientific sources) that an enzyme in sperm causes the embryo to split. Does an Enzyme in Sperm Cause Identical Twins? It is also possible that subtle differences in the cells could force cells to repel one another, pushing two separated groups of cells to opposite sides of the blastocyst. A mutated gene could cause weakened cells in a collapsing blastocyst (ball of cells formed as the fertilized egg grows), triggering a twinning event. This leads to the idea that a similar process could be caused in naturally conceived embryos. He speculates that the mutated gene might prevent cells sticking together tightly within the blastocyst, resulting in a split.ĭr Dianna Payne thinks the imperfect environment of the IVF lab is causing some cells to die or weaken at the cell junctions. 2017.ĭr Reversade has a candidate region, on chromosome four, and he thinks mutations in a gene here might have been present in the founders of twin towns before spreading through the population. Twin Mythconceptions: False Beliefs, Fables, and Facts about Twins. It seems that the genes belong to the ELA (equine lymphocyte antigen) gene system may tell us something about how can run in families. These ‘twin towns’ are relatively isolated with a small breeding pool, allowing the mystery ‘twinning gene’ to be passed on in abundance. Although monozygotic (identical) twinning doesn’t seem to vary by geography or ethnicity, there are small pockets of increased twinning activity. Do Inherited Gene Mutations Cause Monozygotic Twinning?ĭr Bruno Reversade is one scientist who has been busy investigating variations in the genomes of families from ’twin towns’. Non-identical monozygotic twins, intermediate twin types, zygosity testing, and the non-random nature of monozygotic twinning: a review. ![]() However, familial monozygotic twinning is more common than suggested by the literature. Previously, it was thought that MZ twinning was some sort of embryological fluke. We’ve looked at when it happens, but what scientific theories are out there for why identical twins develop from one fertilised egg? Scientific Theories for Why the Fertilized Egg Splits to form Identical Twins ![]()
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